Meeting programme 2025

9.00: Welcome

9.30-11.00: Session 1
Dr. Sarah Lippé: Brain Signals to the Rescue : Advancing Our Understanding of Childhood Neurodiversity
  
Shilpa Anand - Amsterdam UMC: Altered cortical dynamics of spontaneous resting-state EEG oscillations is associated with neurodevelopmental delay in children with rare monogenetic neurodevelopmental disorders 

Nina Doorn - University of Twente: From MEA to EEG and back: A computational approach to translate in vitro iPSC-derived neuronal network findings to in vivo patient phenotypes 
 
Kim Wijnant - Radboud UMC: Long- and short-read RNA sequencing to identify targetable unproductive splicing for gene upregulation in neurodevelopmental disorders 


11.00-11.30 
coffee break
 
11.30-12.30: Session 2
Prof. dr. Michael Ziller - Bridging the scales: Leveraging in vitro models to identify the neurobiological and behavioral consequences of synaptic aberrations in schizophrenia

Dr. Sofia Puvogel   - Radboud UMC: Molecular bases of network activity convergencies in neurodevelopmental disorders: An integrated transcriptomic–functional perspective


12.30-14.00 
Poster Session 1
Lunch break 
 
14.00-15.00 Session 3: Keynote 
Prof. dr. Sergiu Paşca     - From stem cells to assembloids and towards building human circuits in living systems to develop therapeutics ​

15.00-15.30
coffee break
 
15.30- 17.00: Session 4 
Dr. Karun Singh: Using brain organoid-based neural circuits to understand neurodevelopmental disease mechanisms

Torben van Voorst - VU Amsterdam: ​Positional effects of SYT1 missense variants on neurotransmitter and neuropeptide release

Bianca Zardetto - Leiden UMC: Splice-altering strategy in a patient-derived oligodendrocyte cell model for PLP1-associated hypomyelination of early myelinating structures 

Emilio Harris-Mostert - Erasmus MC: Development of Personalized Antisense Oligonucleotide Therapies for Rare Monogenic Neurodevelopmental Disorders 


17.00-18.30  
Poster Session 2
Drinks 



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Local organising committee:
dr. Annelot van Esbroeck Weevers
dr. Katrin Linda
Prof. N. Nadif Kasri


SPONSORS: