The third Dutch neurodevelopmental disorders meeting will be held March 7th 2018 with the aim of bringing together fundamental and clinical researchers working in the Netherlands in the field of neurodevelopmental brain disorders, such as intellectual disability and autistic spectrum disorders.
This one-day meeting aims to present recent results from across the many Institutes and clinics across the country and to stimulate discussion, networking opportunities and potential future collaborations. The meeting will kick-off with a talk from Professor Hans van Bokhoven. The programme is subdivided into 4 sections, featuring junior and senior researchers from across a variety of institutes and clinics across the Netherlands.
Attendance of the meeting is free and open to all but prior registration is required due to limited places. Lunch and refreshments are provided. All talks will be given in English. To register, please send an email with the header 'DNDD2018' to DNDD2018@gmail.com. Registration closes on March 2nd 2018.
Er is een accreditatie aanvraag ingediend bij de NvN, NvK en VKGN. (For clinicians, a request for accreditation has been registered with the NvN, NvK and VKGN).
Meeting programme Date: 7th March 2018 Location: Erasmus Rotterdam
9-9.15h: Introduction and welcome from hosts
KEYNOTE LECTURE: 9.15-10.15
Hans van Bokhoven (Nijmegen): Converging molecular and cellular pathways across neurodevelopmental disorders.
CLINICAL ASPECTS AND GENETICS OF NDDs: 10.15-11.15h
10.15-10.40: Iris Overwater (Rotterdam):Can everolimus treat intellectual disability and autism in children with Tuberous Sclerosis Complex? Results from a randomized, placebo-controlled trial
10.40-11.10: Coffee break
11.10-11.35: Eleonora Aronica (Amsterdam): mTOR pathway-related malformations of cortical development. From Histology to an “Integrated diagnosis”
11.35-12.00: Gijs Santen (Leiden): ARID1B: lessons from 5 years of clinical research
12.00-12.25: Margot Reijnders (Nijmegen):Neurodevelopmental Disorders: a next generation.
12.25-13.30h lunch (provided)
PRECLINICAL MODELS OF NDDs: 13.30-15.00h
13.30- 13.55: Rossella Avagliano Trezza (Rotterdam):To the nucleus and back: UBE3A sub-cellular localisation and its critical role in Angelman Syndrome development
13.55-14.20: Hilde Brems (Leuven): Social behavior deficits in a Spred1 knockout mouse model of Legius syndrome
14.20-14.45: Katrin Linda (Nijmegen):Role of KANSL1 in autophagy in a human model for Koolen-de Vries Syndrome
14.45-15.15 coffee break
THE DEVELOPING BRAIN: 15.30-16.30h
15.15-15.40: Jeroen Pasterkamp (Utrecht): Molecular mechanisms of neural circuit development.
15.40-16.05: Corette Wierenga (Utrecht): A role for plasticity of inhibitory synapses in autism?
16.05-16.30: Femke de Vrij (Rotterdam):Evidence for oligodendrocyte progenitor cell dysfunction in familial schizophrenia.
16.30-16.45: Closing remarks
The meeting will take place in Erasmus MC, Lecture hall 2, in the Education Centre.
Directions can be found here directly: www.erasmusmc.nl/bereikbaarheid